As we age, our cells begin to deteriorate and lose their ability to function properly. This is a natural process that ultimately leads to ageing and the onset of age-related diseases. But what if we could turn back the clock on ageing by getting rid of these old cells?
Recent research suggests that this may be possible. Studies have shown that when old cells are removed, the body is able to replace them with new, healthy cells. This process is known as cell turnover.
One way to increase cell turnover is through a process called autophagy. Autophagy is the process by which cells clean out and recycle old, damaged, or unnecessary materials. When autophagy is activated, cells are able to remove damaged proteins, organelles, and other debris, which in turn allows for the growth and repair of new cells.
Another way to increase cell turnover is through the use of senolytic drugs. Senolytic drugs target and destroy senescent cells, which are cells that have stopped dividing and are no longer able to perform their normal functions. By removing these cells, the body is able to replace them with new, healthy cells.
Both autophagy and senolytic drugs have been shown to have anti-ageing effects in animal studies. For example, mice that were treated with senolytic drugs were able to live longer and were less likely to develop age-related diseases. Similarly, mice that were genetically engineered to have increased autophagy lived longer and were healthier than mice without this genetic modification.
While these findings are promising, more research is needed to fully understand the potential anti-ageing effects of cell turnover. Additionally, it is important to note that these treatments may not be appropriate for all individuals, and more research is needed to determine their safety and efficacy in humans.
Overall, the idea of turning back the clock on ageing by getting rid of old cells is an exciting one. Further research in this area may lead to new treatments and therapies that could help us live longer, healthier lives.
